Chromium picolinate, CAS: 14639-25-9

Chromium picolinate health supplement Picolinic acid Chromium for strengthening muscles 14639-25-9

Product Name: Chromium picolinate,Picolinic acid Chromium

CAS: 14639-25-9
MF: C18H12CrN3O6
MW: 418.3
storage temp. room temp
Chemical Properties: Dark violet crystal

Chromium picolinate is a health supplement for strengthening muscles and promoting weight. It can increase the amount of the active AMP protein kinase (AMPK) related with metabolism pathway inside the skeletal cells, thereby improving energy balance and insulin function. The main effects are as follows:
1, It can improve the proportion of lean meat, reduce fat as well as improve carcass quality.
2, It can improve the capability of stress resistance and immunity. Stress can cause reduced animal production while niacin chromium, through its anti-stress effect, may increase the production of animal products.
Chromium is an essential mineral, it is the indispensable substance for the release of active insulin during the carbohydrates, fat and protein metabolism. In August 2005, the US Food and Drug Administration (FDA) had approved the production of chromium picolinate, and confirmed that it is safe for being applied to the treatment of human insulin resistance and type II diabetes. The main basis for FDA for made this judgment was the early, randomized, and double-blinded and placebo therapy conducted by Dr. Cefalu who had shown that chromium picolinate can significantly improves the insulin sensitivity of the patients of the high-risk diabetic.

Precautions: At present, according the research of domestic and international research institutions and Nutrition Institute, long-term intake of chromium ≥1000ug/day can easily lead to poisoning. The maximal allowable consumption amount for health food is 250ug/day.
1, excess iron and zinc can hinder and inhibit the absorption of chromium.
2, manganese and chromium have mutually reinforcing roles in the regulation of glucose metabolism.
3, chromium and magnesium can synergistically promote the sugar conversion.
4, there is no need for increasing daily sugar protein and lysine levels.

Uses: It can be used as a medicine and health products as well as food additives.
Chromium picolinate (CrPic) is taken as the supplement or alternative medicine for type 2 diabetes. Experimental evidence has indicated CrPic boost glucose uptake via activating P38 MAPK. Chromium is thought to be able to enhance the action of insulin, thereby increasing insulin sensitivity in type 2 diabetes patients