Terbinafine Hydrochloride

描述

Terbinafine Hydrochloride Basic information
Product Name: Terbinafine Hydrochloride
Synonyms: lamosil;n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamin(e)-1-naphthalenemethanaminmon;Lamisil, N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1-naphthalenemethanamine;1-Naphthalenemethanamine, N-(2E)-6,6-dimethyl-2-hepten-4-ynyl-N-methyl-, hydrochloride;TERNBINAFINEHCL;({[(2E)-6,6-Dimethylhept-2-en-4-yn-1-yl](methyl)amino}methyl)naphthalene hydrochloride;Trebinafine hydrochloride;1-(3,5-Dihydroxyphenyl)-2-(tert-butylamino)ethanol
CAS: 78628-80-5
MF: C21H26ClN
MW: 327.89
EINECS: 616-640-4

Standard: EP, pharmaceutical grade
Assay: 99%
Appearance: white crystal
Packaging : 25KG/ cardboard drum
Product Categories: -;Antifungal;APIs;Acetylenes;Antifungals for Research and Experimental Use;Biochemistry;LAMISIL;Functionalized Acetylenes;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Terbinafine

Terbinafine Hydrochloride Usage

Chemical Properties White crystalline powder. Melting point is 204-208 oC.
Usage Terbinafine hydrochloride is a kind of broad-spectrum dermatologist allyl amine antifungal drugs. It has a significant effect on all kinds of tinea diseases , including fungus, trichophyton, ringworm of the body, tinea, tinea versicolor and onychomycosis caused by dermophyte. It can also be used for bronchial asthma, asthmatic bronchitis and emphysema, etc.

Description Terbinafine hydrochloride is the first orally active allylamine antifungal with 30-fold greater antifungal activity than naftifine. The compound is indicated for the treatment of ringworm and fungal nail infections. Terbinatine hydrochloride acts on a single fungal enzyme, squalene epoxidase, interfering with the biosynthesis of ergosterols in cell membranes. Unlike other antifungal agents, it does not inhibit cytochrome P450 enzymes.
Chemical Properties Crystalline Powder

Uses An orally active, antimycotic allylamine related to Naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Antifungal.
Uses Terbinafine hydrochloride is a synthetic allylamine antifungal. It is used to treat dermatophyte infections of the toenail/fingernail, ringworm and jock itch. It is used in adsorption, partition and stability studies.