Indometacin

描述

Indometacin Basic information
Product Name: Indometacin
Synonyms: Indomethacin – CAS 53-86-1 – Calbiochem;AURORA KA-6542;INDOCIN;INDOMETACIN;INDOMETACINE;INDOMETHACIN;INDOMETHACINE;LABOTEST-BB LT00244830
CAS: 53-86-1
MF: C19H16ClNO4
MW: 357.79
Standard: BP, pharmaceutical grade
Assay: 99%
Appearance: white powder
Packaging : 25KG/ cardboard drum
Product Categories: PHARMACEUTICALS;Active Pharmaceutical Ingredients;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Lipid signaling;-;INDOCIN;Other APIs;Pharmaceutical raw chemicals
Chemical Properties Crystalline Solid
Indometacin Usage
usage and dosage 1.Anti-rheumatism: adult dosage: oral: early quantity from 25 to 50 mg each time, 2~4 times a day, immediately take at food service or after a meal. Such as good tolerance, the daily dosage can be increased from 25 to 50 mg per week, the most mount should not be more than 200 mg a day. Arthritis patients such as persistent pain at night or morning stiffness, can give quantity of 100 mg in bed all day.
2. Resistance to gout: oral: At the beginning quantity is 100 mg once, then 50 mg, three times a day, until the pain relief, and then gradually reduced as soon as possible, until the drug withdrawal.
3. Antifebrile: adult dosage: oral: 25~50 mg each time, 3~4 times daily.Rectal drug delivery: every time 50 mg, 50 to 100 mg per day. Pediatric dosage: oral: 0.5~1 mg/kg each time, 3 times a day.
The above information is Chemicalbook Hanya edited.

Uses Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD
Uses antiinflammatory, antipyretic, analgesic