Follistatin-344

描述

Peptide Follistatin-344 Lyophilized powder Human growth hormone human growth hormone releasing peptide FST 344 for Bodybuilding

Description of Follistatin 344
Unit Size: 1mg/vial
Appearance : Lyophilized white powder
Specific Optical Rotation (c=0.5,10% HAc) :-50.0~-60.0°
Water Content(Karl Fischer) : ≤5.0%
Acetate Content(by HPLC) : ≤15.0%
Amino Acid Composition : ±10% of theoretical
6Purity (by HPLC) :≥98.0%
Single Impurity(by HPLC) :≤1.0%
Peptide Content(by %N) : ≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins : ≤5EU/mg
What is Follistatin ?
Follistatin (follistatin) is known as an autocrine activin-binding glycoprotein that is produced almost all tissues of the body. This peptide encoded by the gene, and FST directly combats myostatin. As we know, that myostatin – a bodybuilder enemy №1 in Europe.

The key regulatory factor myostatin-follistatinovoy systems are myostatin – a potent endogenous inhibitor of muscle growth and its physiological blocker – follistatin. Increasing the concentration of myostatin in the body is the immediate cause of age and hereditary muscular dystrophy, a genetic defect in the gene for myostatin, on the contrary, lead to the appearance of individuals with increased muscle mass. Available online data suggest that reducing myostatin using Follistatin 344 (follistatin) does not lead to undesirable health consequences, so the impact aimed at the removal from the body of myostatin may be promising in the treatment of muscular dystrophy and in sports medicine, and in zootechnics. FST significantly accelerates muscle growth!

Myostatin – synthesized within body a protein that inhibits the growth and differentiation of muscle tissue. Miostitan formed in the muscles and then released into the bloodstream, providing its effect on muscle by binding to receptors ACVR2B (activin type II receptor). Myostatin yakloveka encoded in a gene MSTN and studies show that blocking the action of myostatin peptide Follistatin 344 leads to a significant increase in lean body mass with an almost complete absence of fat in a short time. Good reason to buy it.

Application :
Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle-stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an N-terminal atypical TGF binding domain, three Follistatin domains that contain EGF-like and kazal-like motifs, and a highly acidic C-terminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids.

The recommended duration of the course of 30 days.
Total vials on one course – 2 Follistatin 344 vial to 1 mg of active ingredient each. Makes 1 injection per day in the morning for 100 mcg subcutaneously in the abdominal oblique muscles. Peptide may be used locally. There are versions that in this e the drug increases the target muscle to a greater extent than others. After 10 days of use is the same 10-day break. After this break, it is recommended to start a new 10-day cycle.

Solubility of Follistatin 344 on course:
It is recommended to add 2 ml of water for injection in a bottle and wait until complete dissolution of the lyophilized pellet. In this embodiment, the dilution, the required dosage of us peptide 100 micrograms, is at the level of “20” insulinki. Let me remind you, we use only 100ed insulinki!

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