Diclofenac sodium

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Description

Diclofenac sodium Basic information:

Name: Diclofenac sodium
CAS: 15307-79-6
MF: C14H10Cl2NNaO2
MW: 318.13
Standard: BP
Purity: Pharmaceutical grade 99%
Appearance: white powder
chemical properties: White or almost white, odorless, easy to absorb the crystalline powder, the product by inhibiting cyclooxygenase thereby reducing prostaglandin synthesis. Commonly used in its sodium salt, colorless crystals, odorless, soluble in water, ethanol and other polar organic solvents, pH = 7.68 aqueous solution, pKa = 4. Melting point 283-285 ° C.

Packing: 25KG / Fiber drum
Uses A nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor.
Uses An inhibitor of Cox-1 and Cox-2.

Diclofenac sodium Indications:

1, ease rheumatoid arthritis, osteoarthritis. Spondyloarthropathies, gouty arthritis, rheumatoid arthritis and other chronic exacerbation of chronic arthritis or persistent symptoms of joint swelling and pain;

2, all kinds of soft tissue rheumatic pain, such as shoulder pain, tenosynovitis, bursitis, bursitis and post-traumatic pain;

3, acute mild to moderate pain, such as: surgery, trauma, strain after pain;

4, primary dysmenorrhea, toothache, headache and so on.

Dosage:

oral:
Adult rheumatoid arthritis 150mg ~ 200mg / day, 2 times to 4 times service up to gradually reduce the minimum effective dose, usually 75mg ~ 100mg / day, taking 3 times;

Osteoarthritis start 100mg ~ 150mg / day, 2 times to 3 times service up to the effective gradually reduced to the minimum effective dose;

Ankylosing spondylitis 100mg ~ 125mg / day, 4 times to 5 times service, up to the effective dose gradually reduced to the minimum effective dose;

Children (1 year old) daily by body weight 0.5mg ~ 2mg / kg, 2 times to 3 times service.

Adverse reactions:

Abdominal pain, diarrhea, nausea, indigestion, bloating, vomiting, gastritis, constipation, rash, dizziness, headache, menorrhagia. Patients with liver disease may appear S-GPT, S-GOT and bilirubin increased. Occasionally kidney damage

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