Dextran

描述

Dextran Basic information
Product Name: Dextran
Synonyms: dextran5;DextrangradeA,B,C;dextrans;Dextraven;Ex-pandex;Gentran3;Hemodex;Intradex
CAS: 9004-54-0
MF: C17H32O10
MW: 396.42998
Standard: Pharmaceutical grade
Appearance: white powder
Packaging: 25/ cardboard drum
Product Categories: Dextrins、Sugar & Carbohydrates;Carbohydrates D-FAlphabetic;DA – DHBiochemicals and Reagents;Biostabilization AgentsCarbohydrates;Biostabilization AgentsBiochemicals and Reagents;Carbohydrates A to;Carbohydrates D-FBiochemicals and Reagents;Biochemicals and Reagents;Carbohydrates;Polysaccharide;DA – DHPolymer Standards;Alphabetic;D;Dextran;Water Soluble Polymers;DextranChromatography;DIN StandardsCertified Reference Materials (CRMs);Application CRMs;Polymer Standards;Biostabilization AgentsResearch Essentials;CarbohydratesBiochemicals and Reagents;Stabilization of Biomolecules;Core Bioreagents;Organic SolublePolymer Standards;Polymer Standards Kits;Water Soluble;Cell Separation (Centrifugation) MediaResearch Essentials;Centrifugation Media;Hematology and Histology;Carbohydrates & Derivatives;-;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Other APIs
Dextran Usage
Description Dextran, a glucose polymer composed predominantly of ol-1,6-glucopyranosidic linkages, is produced from sucrose by Leuconostoc mesenteroides and related organisms and from dextrins by other bacteria.
Dextran is used in a bead form to aid in bioreactor applications, some size-exclusion chromatography matrices and in osmotic stress technique study involved in biological molecules. It can be used as a stabilizing coating to protect metal nanoparticles from oxidation.
Dextrans are long-chain glucose polysaccharides of various relative molecular masses. Dextran 70 (relative molecular mass 70 000) is retained in the intravascular space where, like albumin, it contributes to the colloid oncotic pressure of plasma. Unlike albumin, dextran 70, when given in large amounts, prevents platelet aggregation and facilitates fibrinolysis.

Chemical Properties white crystals or powder
Uses Dextran is a polysaccharide composed of glucose molecules used as an antithrombotic to reduce blood viscosity and as a volume expander in anemia. Studies show that it inhibits the mannose receptor-med iated clearance of tissue-type plasminogen activator (t-PA).
Uses also available in pharma grade
Uses exhibit borad spectrum of biological activities, with very low anticoagulant capacity: they activate lipoprotein elimination by lipase stimulation, inhibit cell proliferation in vascular wall, regulate transport of plasmatic proteins and inhibit depositi
Uses antiinflammatory veterinary drug
Uses dextran is a polysaccharide with water-binding properties. It is also used to control product viscosity. Some studies indicate a capacity to enhance the anti-aging activity of formulations containing weak acids, as well as to reduce possible skin irritation arising from such acids.

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