Premixed Excipient Formulations for Steroids Tablet

Premixed Excipient Formulations for Steroids Tablet

Tablet is an solid dosage form which consist of one or more active ingredient with excipients.Excipients are very important part of the tablet formulation,they are pharmacologically inactive substances included in the formulation which is used as a carrier of active ingredient.Here are examples of the ready mix tablet binder with excipients premixed formula and percentage of each item:

1) A simple and cost effective Pre-Mixed Binder Formula.  

This formula contains 2 basic but very effective excipients – Microcrystalline Cellulose USP and Magnesium Stearate NF.  Microcrystalline Cellulose has a very high binding capability and creates tablets that are extremely hard, stable, yet disintegrate rapidly.  Magnesium Stearate is a popular lubricant because it also acts as a glidant and anti-adherent.
Contains:
Microcrystalline Cellulose USP (98.4%) – binder.
Magnesium Stearate NF (1.6%) – lubricant.

(Note:MCC USP102 has larger particles which are more round and dense.  It is not as fluffy and light as MCC USP101, therefore MCC USP102 has better flow properties than MCC USP101.)

2) A premium, top of the line, pre-mixed excipient formula. 

It is mixed with a high performance tablet lubricant which is not sensitive to over-mixing when active ingredients are added. This powder formula has excellent flow properties and will not stick to punches. Pressed tablets are shiny and very hard, yet disintegrate very rapidly.
Contains:
Microcrystalline Cellulose USP (89%) – main excipient.
Copovidone USP (5%) – sustained release agent / hardener.
Croscarmellose Sodium NF (3%) – disintegrant.
Precipitated Silica USP (2%) – glidant / anti-adherent.
Sodium Stearyl Fumarate NF (1%) – high performance tablet lubricant.

3) A premium, top of the line, pre-mixed excipient formula. 

It is mixed with a high performance tablet lubricant which is not sensitive to over-mixing when active ingredients are added. This powder formula has excellent flow properties and will not stick to punches. Pressed tablets are shiny and very hard, yet disintegrate very rapidly.
Contains:
Microcrystalline Cellulose USP (87%) – main binder.
Copovidone USP (5%) – sustained release agent / hardener.
Croscarmellose Sodium NF (3%) – disintegrant.
Silicon Dioxide USP (2%) – glidant / anti-adherent.
Sodium Stearyl Fumarate NF (1%) – high performance tablet lubricant.
FD&C Blue #1 (2%)

4) A premium, top of the line, pre-mixed excipient formula. 

It is mixed with a high performance tablet lubricant which is not sensitive to over-mixing when active ingredients are added. This powder formula has excellent flow properties and will not stick to punches. Pressed tablets are shiny and very hard, yet disintegrate very rapidly.
Contains:
Microcrystalline Cellulose 101 USP (84%) – main binder.
Copovidone USP (5%) – sustained release agent / hardener.
Croscarmellose Sodium NF (3%) – disintegrant.
Silicon Dioxide USP (2%) – glidant / anti-adherent.
Sodium Stearyl Fumarate NF (1%) – high performance tablet lubricant.
FD&C Blue #2 (5%)

5) A premium, top of the line, pre-mixed excipient formula. 

It is mixed with a high performance tablet lubricant which is not sensitive to over-mixing when active ingredients are added. This powder formula has excellent flow properties and will not stick to punches. Pressed tablets are shiny and very hard, yet disintegrate very rapidly.
Contains:

Microcrystalline Cellulose USP (84%) – main binder.
Copovidone USP (5%) – sustained release agent / hardener.
Croscarmellose Sodium NF (5%) – disintegrant.
Silicon Dioxide USP (2%) – glidant / anti-adherent.
Sodium Stearyl Fumarate NF (1%) – high performance tablet lubricant.
FD&C Red #40 (3%)

6) A premium, top of the line, pre-mixed excipient formula. 

It is mixed with a high performance tablet lubricant which is not sensitive to over-mixing when active ingredients are added. This powder formula has excellent flow properties and will not stick to punches. Pressed tablets are shiny and very hard, yet disintegrate very rapidly.
Contains:
Microcrystalline Cellulose USP (84%) – main binder.
Copovidone USP (5%) – sustained release agent / hardener.
Croscarmellose Sodium NF (3%) – disintegrant.
Silicon Dioxide USP (2%) – glidant / anti-adherent.
Sodium Stearyl Fumarate NF (1%) – high performance tablet lubricant.
FD&C Yellow #5 (5%)

Posted in Homebrew steroids guide.

Leave a Reply

Your email address will not be published. Required fields are marked *