Category Archives: Weight Loss

1,3-dimethylamylamine (DMAA), CAS: 13803-74-2

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DMAA 1,3-dimethylamylamine Weight Loss Steroids 4-Methyl-2-Hexanamine Hydrochloride food supplements

Quick details:

Product Name:4-Methyl-2-Hexanamine Hydrochloride
CAS: 13803-74-2
MF: C7H17N.HCl
MW: 151.68
Appearance: White crystalline powder
Smell: Smellless
Chemical Properties White Solid
Usage: 1,3-Dimethylpentylamine is useful in compositions, for example as dietary supplements, and for appetite suppression.
Product Categories: Pharmaceutical Intermediates;Aliphatics;Amines;Intermediates & Fine Chemicals; Pharmaceuticals

Description:

1,3-dimethylamylamine is a derivative of geranium oil which resembles the body’s own chemical messenger
1,3-dimethylamylamine exihibits a powerful CNS stimulanting ability, for increased energy, mental clarity, and physical performance.
1,3-dimethylamylamine works through a similar pathway as ephedrine, causing an increase in cAMP (the chemical messenger that triggers fat release and provides potent appetite suppression and thermogenic action).

4-Methyl-2-hexanamine hydrochloride Applications:

1. Improve Menopausal problem.
2. Has the characteristics of geranium diuresis, can help to liver, kidney discharges poison.
3. Stimulate lymph system to avoid infection, eliminate waste. Strengthen circulation system, make cycle more smooth.
4. A kind of sweet the insect repellent
5. It is used in nasal decongestants and nutritional supplements.
6. It is widely used in energy supplement for weight loss and bodybuilding.
7. It can be take as health care products,increasing energy, refreshing, and improving the body’s energy.
8. It can increase the physical fitness, improve concentration, significantly suppress appetite, curb hyperactive

Usage:

Dimethylpentylamine has been recently used in energy supplements for weight loss and bodybuilding, as well as for substances that are amphetamine-like. More notably, Dimethylpentylamine was used in AMP2 and AMP energy supplements, of which are considered by their developer as having low side effects in comparison to ephedrine. See how Phentramin-D uses a different kind of Hydrochloride in its weight loss arsenal to help you lose the weigtht and keep it off. DMAA is an effective central nervous system stimulant. Its main function are sumarrized as increase energy, improve mood, burn fat, and suppress appetite, and most importantly, as a wild stimulant.

Lorcaserin Hydrochloride, CAS: 856681-05-5

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Lorcaserin hcl Weight Loss Powder Lorcaserin Hydrochloride 856681-05-5

Product Name: (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine hydrochloride hemihydrate
CAS: 856681-05-5
MF: 2(C11H14ClN).2(HCl).H2O

Lorcaserin, currently marketed under the trade name Belviq and previously Lorqess during development, is a weight-loss drug developed by Arena Pharmaceuticals. It has serotonergic properties and acts as an anorectic.

Lorcaserin Medical uses

Lorcaserin is used long term for weight loss in those who are obese.

Lorcaserin Side effects

In clinical trials, the most common side effect was headache, experienced by about 18% of drug arm participants compared to 11% of placebo participants. Headache was the only reported side effect to occur at a frequency greater than 5 percentage points above those from placebo. Other reported side effects and their rates for lorcaserin and placebo patients, respectively, were as follows: upper respiratory tract infection (14.8% vs. 11.9%), nasopharyngitis (13.4% vs. 12.0%), sinusitis (7.2% vs. 8.2%), and nausea (7.5% vs. 5.4%). Adverse events of depression, anxiety, and suicidal ideation were infrequent and were reported at a similar rate in each treatment group.
On 15 September 2010 it was reported by national news media that lorcaserin was associated with the development of cancer in laboratory rats.[7]
In December 2012, the US Drug Enforcement Administration proposed classifying lorcaserin as a Schedule IV drug because it has hallucinogenic properties at higher than approved doses and users could develop psychiatric dependencies on the drug.[8][9] On 7 May 2013, the US Drug Enforcement Administration classified lorcaserin as a Schedule IV drug[10] under the Controlled Substances Act.[8]
There has been concern that lorcaserin can cause cardiac valvulopathy based upon the reports of subjects taking the drug in Phase 2 trials. However, a Phase 3 clinical trial of the drug was conducted and the results published in the October 2014 Postgraduate Medicine journal, a peer-reviewed medical journal for physicians. These results found no statistically significant differences in valvulopathy rates compared to control, being 2.4% for the drug subjects and 2.0% for controls.

Synephrine hydrochloride, CAS: 5985-28-4

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Synephrine hydrochloride without side effect Synephrine hcl for weight loss 5985-28-4

Product Name: Synephrine hydrochloride
CAS: 5985-28-4
MF: C9H14ClNO2
MW: 203.67
Purity: 99%
EINECS: 227-804-6
Appearance: white powder
Usage : A α-adrenergic receptor agonist, vasoconstrictor.

INFORMATION ON SYNEPHRINE HCL:

Synephrine HCL is a weight loss ingredient that is found in Citrus Arantium fruit called bitter orange. This is the reason Synephrine HCL is largely found as an ingredient in many dietary supplements for weight loss. Synephrine HCL is having similarity with ephedrine though not as potent as ephedrine is.

Use of Synephrine HCL does not involve any legal issue being a dietary supplement.As already said synephrine was began to use as an alternative to ephedrine and synephrine has got almost the same benefits to that of ephedrine but its side effects are drastically lesser than ephedrine. Important health benefits of synephrine include- deceasing appetite, increasing metabolism, burning fat, promoting weight loss, increasing alertness and increasing energy and body heat. More importantly synephrine has been proved to be a remarkable substance that helps people in losing weight. Through its benefits of increasing energy and the degree of alertness, synephrine improves the ability of a person to do more and more exercise as a part of his weight loss plan. Similarly, decreased appetite and increased metabolism make the diet plan for weight loss a success. All these facilitate in contributing to the weight loss. Similarly important side effects of synephrine consumption may includes headache, nausea, increased HR anxiety, insomnia, and upset stomach. This apart as synephrine is a stimulant just like caffeine, people having heart problems must not take any product that has got synephrine HCL in it. The most important aspects of the side effects of synephrine are that they are very minor in nature and can be avoided if proper care and caution is taken while taking this and the same invariably should not be taken beyond the prescribed level.

Function of synephrine hydrochloride:

1. synephrine hydrochloride providing an energy boost, suppressing appetite
2. synephrine hydrochloride increasing metabolic rate and caloric expenditure
3. synephrine hydrochloride causes the breakdown of fat without affecting blood pressure or heart rate
4. synephrine hydrochloride treat chest congestion and indigestion
5. synephrine hydrochloride stimulate gastrointestinal functions, and improve circulatory and
liver functions.

Chromium picolinate, CAS: 14639-25-9

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Chromium picolinate health supplement Picolinic acid Chromium for strengthening muscles 14639-25-9

Product Name: Chromium picolinate,Picolinic acid Chromium

CAS: 14639-25-9
MF: C18H12CrN3O6
MW: 418.3
storage temp. room temp
Chemical Properties: Dark violet crystal

Chromium picolinate is a health supplement for strengthening muscles and promoting weight. It can increase the amount of the active AMP protein kinase (AMPK) related with metabolism pathway inside the skeletal cells, thereby improving energy balance and insulin function. The main effects are as follows:
1, It can improve the proportion of lean meat, reduce fat as well as improve carcass quality.
2, It can improve the capability of stress resistance and immunity. Stress can cause reduced animal production while niacin chromium, through its anti-stress effect, may increase the production of animal products.
Chromium is an essential mineral, it is the indispensable substance for the release of active insulin during the carbohydrates, fat and protein metabolism. In August 2005, the US Food and Drug Administration (FDA) had approved the production of chromium picolinate, and confirmed that it is safe for being applied to the treatment of human insulin resistance and type II diabetes. The main basis for FDA for made this judgment was the early, randomized, and double-blinded and placebo therapy conducted by Dr. Cefalu who had shown that chromium picolinate can significantly improves the insulin sensitivity of the patients of the high-risk diabetic.

Precautions: At present, according the research of domestic and international research institutions and Nutrition Institute, long-term intake of chromium ≥1000ug/day can easily lead to poisoning. The maximal allowable consumption amount for health food is 250ug/day.
1, excess iron and zinc can hinder and inhibit the absorption of chromium.
2, manganese and chromium have mutually reinforcing roles in the regulation of glucose metabolism.
3, chromium and magnesium can synergistically promote the sugar conversion.
4, there is no need for increasing daily sugar protein and lysine levels.

Uses: It can be used as a medicine and health products as well as food additives.
Chromium picolinate (CrPic) is taken as the supplement or alternative medicine for type 2 diabetes. Experimental evidence has indicated CrPic boost glucose uptake via activating P38 MAPK. Chromium is thought to be able to enhance the action of insulin, thereby increasing insulin sensitivity in type 2 diabetes patients

Calcium pyruvate, CAS: 52009-14-0

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Hot selling Calcium Pyruvate Weight Loss Steroids Pharmaceutical Raw powder 52009-14-0

Product Name: Calcium pyruvate
Synonym: Pyruvic acid Calcium salt; Pyruvic acid calcium
CAS: 52009-14-0
MF: C6H6CaO6
MW: 214.19
EINECS: 257-599-9
Appearance: White to light yellow powder
Purity: 99%
Grade: Pharmaceutical Grade

Overview

Calcium pyruvate is a natural substance made in our bodies that contributes to metabolism and the digestion of carbohydrates. The unstable form of this substance, known as pyruvic acid, is stabilized by the addition of sodium or calcium. Calcium pyruvate is the compound that starts the Kreb’s Cycle, by which our bodies make adenosine triphophate (ATP) or energy during aerobic respiration. Aerobic respiration is that which occurs in the presence of oxygen, during exercises, such as running and jogging. Natural sources of pyruvate include apples, cheese, dark beer and red wine.

Fat Loss

Calcium pyruvate can enhance exercise endurance, increase cell energy, prevent or reduce due to too much caused by the consumption of fat and increase in body weight, heart, muscle inhibition efficiency, reduce the high fat fed cholesterol.

Pyruvate is a 3-carbon energy intermediate produced in cells from glucose, en route to creating ATP (the main energy currency of working cells). Pyruvate supplementation has been proposed to enhance work output and weight loss by providing more efficient energy that bypasses the ability of the body to store glucose as body fat.

Many claim that calcium pyruvate can help with weight and/or fat loss. In theory, since it is the raw material for cellular respiration, supplementing with calcium pyruvate should increase the amount of energy burned, therefore allowing for more fat burning. The question is whether this is actually the case. A study done by Dr. Ronald Stanko at the University of Pittsburgh concluded that calcium pyruvate does have this fat burning effect. Obese women were put on a 1,000-calorie diet for 21 days during this study. The group receiving calcium pyruvate experienced 48 percent higher fat loss, amounting to 3.2 extra pounds. However, very large doses of 30 grams per day were used to elicit this result. The common recommendation of 5 grams per day may not be enough to produce similar results. The expense of high dosage supplementation with calcium pyruvate may be too expensive for some. Diet-and-Health.net discounts the research, claiming that there is still no solid evidence for weight loss benefits.

Application

1. Calcium pyruvate as dietary supplements, has accelerated fat consumption, reduce weight, enhance human endurance, improve the efficacy of athletic performance etc.
2. A special protective effect on the heart, can enhance the effectiveness of the heart muscle, causing a reduction in heart disease or cardiac ischemia injury.

3. At the same time, calcium pyruvate engulfed in a free radicals and inhibit the formation of free radicals and other significant effects.

4.Some suggest that other potential benefits of calcium pyruvate supplementation may include antioxidant activity for antiaging, lower blood pressure and cholesterol, increased glyogen storage and utilization,
Effective Dose

The effect of calcium pyruvate may be dependent on the dose, and if you’re dieting when you take it. In the “American Journal of Clinical Nutrition” study, participants who took 30 grams of pyruvate, 16 grams of which was calcium pyruvate, were on restricted diets. Pyruvate accounted for 13 percent of the participants’ diets. In the study published in “Nutrition,” which did not find significant effects for pyruvate, participants maintained their normal diets and took 5 grams of calcium pyruvate twice a day.

L-Carnitine, CAS: 541-15-1

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L-Carnitine healthy Natural Nutrient Vitamin BT Carnitine Powder Weight Loss Steroids 541-15-1

L-Carnitine

CAS: 541-15-1
MF: C7H15NO3
MW: 161.2
EINECS: 208-768-0
Chemical Properties: White crystalline
Usage: antimethemoglobinemic, cyanide antidote
Essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthetized primarily in the liver and kidney; highest concentrations f ound in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado.

Product description:

L-Carnitine is an amino acid which has a role to play in the body’s fat metabolism process. L-Carnitine transports fatty acids to the mitochondria, which is where they are essentially burned as fuel. This amino acid naturally occurs, although it can also be biosynthesized from two other ones. In addition to being found in a wide range of foods, it is also commonly available as a dietary supplement.

Application:

Essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthetized primarily in the liver and kidney; highest concentrations f ound in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado.
L-Carnitine is a natural, vitamin-like nutrient wich plays an important role inhuman metabolism. It is essential in the utilization of fatty acids and in transporting metabolic energy

Carnitine burns body fat:

Carnitine has an essential role in transporting fat into mitochondria (the furnace of the cell). Therefore, carnitine has been marketed as a fat burning supplement.Carnitine is a substance that helps the body turn fat into energy. Your body makes it in the liver and kidneys and stores it in the skeletal muscles, heart, brain, and sperm.

Usually, your body can make all the carnitine it needs. Some people, however, may not have enough carnitine because their bodies cannot make enough or can’t transport it into tissues so it can be used. Some other conditions, such as angina or intermittent claudication, can also cause low levels of carnitine in the body, as can some medications.

Carnitine has been proposed as a treatment for many conditions because it acts as an antioxidant. Antioxidants fight harmful particles in the body known as free radicals, which damage cells and tamper with DNA. Antioxidants can neutralize free radicals and may reduce or help prevent some of the damage they cause.
burns body fat

L-Carnitine Usage:

1. L- carnitine is supplement our new approved the use of animal nutrition. Mainly used for reinforcement additive protein based, can promote the absorption and utilization of fat. D type and DL type no nutritional value. The use of 70-90mg/kg. 68gL- carnitine).

2. L- carnitine is our country new approved the use of food supplements. Mainly used in the soy based infant food, promote fat absorption and utilization. D- type and DL- type no nutritional value. D- type and DL- type no nutritional value. Our country law can be used for biscuits, drinking liquor and beverage, use the weight of 600~3000mg/kg; On the solid beverage, oral liquid and capsule with 250 ~ 600mg/kg in milk powder; Used in the volume of 300 to 400mg/kg; In infant formula food use amount is 70 ~ 90mg/kg (L- carnitine meter, 1g tartaric acid salt is equivalent to 0.68gL- carnitine).

3. For the appetizer, pharmaceutical, nutritional health products, functional beverages, feed additives

Synephrine, CAS: 94-07-5

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Synephrine Fast Fat Burning Steroids Synephrine no side effect for Anti-obesity 94-07-5

Synephrine

CAS: 94-07-5
MF: C9H13NO2
MW: 167.21
EINECS: 202-300-9
Chemical Properties: Off-White to Beige Powder
Storage: Store in a cool, dry place and keep away from direct strong light. 94-07-5
Shelf Life: 2 years.
Usage: A α-adrenergic receptor agonist, vasoconstrictor.
Usage :anti-obesity
Usage: A a-adrenergic receptor agonist, vasoconstrictor.

Description:

Synephrine is mainly extracted from a fruit citrus aurantium (Citrus aurantium) in. Included in the three Nordic Pharmacopoeia and the German Pharmacopoeia. Natural stimulant synephrine is the 21st century, without any side effects and positive response, widely used in medicine, food, beverage and other health-care industry, with the banned chemical synthetic drugs, synephrine demand and value will be doubled.

Synephrine is lime fruits of the main active ingredient, which can effectively prevent excess energy (heat accumulation), by the wind qi,warm the stomach stimulates the appetite and speeds up metabolism.It is also a mild fragrance expectorant agent, a neurological tranquilizers and laxative treatment of constipation. Users can expect variable effects include consumption of excess calories, reduce appetite and increase satiety, these are likely to lead to weight loss.

Function:

Synephrine is lime fruits of the main active ingredient, which can effectively prevent excess energy (heat accumulation), by the wind qi, warm the stomach stimulates the appetite and speeds up metabolism. It is also a mild fragrance expectorant agent, a neurological tranquilizers and laxative treatment of constipation. Users can expect variable effects include consumption of excess calories, reduce appetite and increase satiety, these are likely to lead to weight loss.

With the function of antibacterial and anti-fungi, it can resist various bactirier, such as staphylococcus aureus, Escherichia coli, typhoid bacillus;With the function of lowering blood cholesterol, reducing thrombosis, improving micro-circulation and nutrient supply, it can effectively prevent cerebrovascular diseases.
At the same tiame, it has the function of spasmolysis and cholagogue, anti-inflammatory and sedative; and the function of anti-cancer, aldose reductase inhibitory effect of the eye.

Cetilistat, CAS: 282526-98-1

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Cetilistat Efficient Weight Loss drug Cetilistat White powder Treating Obesity 282526-98-1

Product Name: Cetilistat
CAS: 282526-98-1
MF: C25H39NO3
MW: 401.58
Chemical Properties: Off-white Cryst
Usage: A novel pancreatic lipase inhibitor for the treatment of obesity in both diabetic and non-diabetic patients.

Cetilistat Description:

Cetilistat is a drug designed to treat obesity. It acts in the same way as the older drug orlistat (Xenical) by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested
In human trials, cetilistat was shown to produce similar weight loss to orlistat, but also produced similar side effects such as oily, loose stools, fecal incontinence, frequent bowel movements, and flatulence.It is likely that the same precautions would apply in that absorption of fat-soluble vitamins and other fat-soluble nutrients may be inhibited, requiring vitamin supplements to be used to avoid deficiencies.
Cetilistat has completed Phase 1 and 2 trials in the West and is currently in Phase 3 trials in Japan where it is partnered with Takeda.[4] Norgina BV has now acquired the full global rights to cetilistat from Alizyme after the latter went into administration.[5]
A published phase 2 trial found cetilistat significantly reduced weight with and was better tolerated than orlistat.

Orlistat, CAS: 96829-58-2

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Healthy Orlistat Weight Loss steroids drug without side effect Orlistat powder fat burning 96829-58-2

Quick Details:

Product Name: Orlistat
CAS: 96829-58-2
MF: C29H53NO5
MW: 495.73
Appearance: White crystalline powder
Purity: 99.51%
Standard: USP
Use: An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent. Antidiabetic;Orlistat is an antiobesity agent. Orlistat is an pancreatic lipase inhibitor. Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin acts as a potent, irreversible inhibitor of pancreatic lipase. In vivo, it blocks the absorption of triglycerides while allowing fatty acid absorption. Tetrahydrolipstatin is widely used for the treatment of obesity.

What is orlistat?

Orlistat blocks some of the fat that you eat, keeping it from being absorbed by your body.

Orlistat is used to aid in weight loss, or to help reduce the risk of regaining weight already lost. This medicine must be used together with a reduced-calorie diet. Orlistat is for use only in adults.

It is dangerous to purchase orlistat on the Internet or from vendors outside of the United States. Medications distributed from Internet sales may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. Samples of “alli” purchased on the Internet have been found to contain sibutramine (Meridia), a prescription weight loss medication that can have dangerous side effects in certain people.

Fat Loss Mechanism

Orlistat is a drug that promotes loss of weight by preventing the digestion and absorption of fat in food. In the intestine, an enzyme called lipase (produced primarily by the pancreas) breaks apart fat in food so that it can be absorbed into the body. Orlistat blocks the action of lipase and thereby prevents the breakup and absorption of fat. Orlistat blocks absorption of about 25% of the fat in a meal. The unabsorbed fat is excreted in the stool.

This medication is used along with a doctor-approved reduced-calorie diet, exercise, and behavior modification program to help significantly overweight (obese) persons lose weight. Taking orlistat can also help prevent you from regaining the weight you have lost. Losing weight and keeping it off can reduce the many health risks that obesity causes, including heart disease, diabetes, high blood pressure, some forms of cancer, certain breathing problems, and a shorter life span.

Dietary fats need to be broken down into smaller pieces before the body can absorb them. Orlistat works by blocking the enzyme that breaks down fats in your diet. This undigested fat then passes out of your body in your bowel movement. Orlistat does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories.

Fat Loss Effect

Orlistat is used for the treatment of obesity. The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body fat.After orlistat was stopped, a significant number of subjects regained weight-up to 35% of the weight they had lost.

The incidence of type 2 diabetes in an obese population over four years is decreased with orlistat (6.2%) compared to placebo (9.0%).Long-term use of orlistat also leads to a modest reduction in blood pressure (mean reductions of 2.5 and 1.9 mmHg in systolic and diastolic blood pressure respectively).

Orlistat Dosage

Orlistat is usually taken 3 times a day during every meal containing fat. The average dosage is a 120mg per day. Due to the fact that Xenical may decrease the absorption of vitamins and it is useful to take a multivitamin once a day at bedtime. While taking this drug bodybuilders and athletes should follow their diet, medication, and exercise routines very closely.

Rimonabant, CAS: 168273-06-1

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Rimonabant Acomplia Weight Loss steroid Powder for fat burning CAS 168273-06-1

Product Name: Rimonabant
CAS: 168273-06-1
MF: C22H21Cl3N4O
MW: 463.79
Usage: Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane

Descriptions:

(1) Rimonabant hydrochloride (SR-141716A) is a potent and selective CB1 cannabinoid inverse
agonist/antagonist with a Ki of 1.6 nM, minimal affinity for CB2, and and some GPR55 agonist activity.
Rimonabant was developed as an anti-obesity drug because of its appetite suppressant activity,
but was taken off the market because of side effects of depression and anxiety.

(2) Under development by Sanofi-Aventis, Acomplia (rimonabant) is a selective CB1 endocannabinoid
receptor antagonist indicated for the treatment of obesity.

(3) It works by blocking endogenous cannabinoid binding to neuronal CB1 receptors. Activation of
these receptors by endoegenous cannabinoids, such as anadamide, increases appetite. It is the most
advanced endocannabinoid receptor antagonist in clinical development and offers a novel therapeutic
approach to appetite control and weight reduction.

Applications:

(1) Rimonabant has a favorable safety profile and is generally well tolerated. Rimonabant is proving to
be a very promising approach for managing two major and preventable risk factors for cardiovascular
disease. This review summarizes the available evidence on the clinical efficacy and safety of
rimonabant as a potential therapy for obesity and smoking cessation.

(2) Rimonabant hydrochloride also has potential as a treatment for smoking cessation because the
endocannabinoid system is involved in the body’s response to tobacco dependence.